It was at this time that the Vaikkom satyagraha began, which attracted widespread national attention. It was launched to give the low-caste people the right to walk on the public road leading to the temple, to which they had been denied entry. The Vaikom satyagraha is very important among the peaceful struggles marked the beginning of the end of untouchability in Kerala. Gurudev blessed the satyagrahis and gave for their use the Vellur Mutt at Vaikom which was then at his disposal.

The prime force behind the Vaikom satyagraha was Gurudev's beloved disciple, the patriot, T.K. Madhavan. In September 1924 Gurudev visited the satyagraha ashram and blessed the Satyagrahis.

The launch of this satyagraha saw Mahatma Gandhi come to Kerala for the first time. He came to Sivagiri and called on Gurudev. That visit helped him greatly to correct his rather orthodox notions about caste system. Afterwards he told a meeting at Trivandrum that it was his good fortune to have met Gurudev.

Gandhiji visited Kerala twice after Sree Narayana Guru's mahasamadhi. On these occasions (in 1934 and 1937) he came to Sivagiri and offered obeisance to the memory of the Guru.

In a speech made at Sivagiri in 1937 Gandhiji said, "I realized clearly that the words of Sree Narayana Guru came from the tongue of a true saint. I studied them with reverence. I have accommodated them as far as I could."On September 27, 1927 at Sarada Mutt at Sivagiri Guru anointed his beloved disciple Sree Bodhananda Swamikal as his successor. In October 1925 Gurudev laid the foundation stone for the Brahma Vidyalaya at Sivagiri.

In May 1926 Gurudev made his will and testament. According to this will, which was conceived in a democratic-spirit, the succession rights to all his movable and immovable properties are vested with the groups of sanyasins who belong to the line of his disciples. Necessary legal provisions for this purpose have been incorporated into the will.In 1926 Gurudev's beloved disciple Sree Sathyavratha Swamikal attained samadhi. Sathyavratha Swamikal who took the message of Sree Narayana Guru to the hearts of the people was an extraordinarily powerful orator and organizer who had received Gurudev's blessings in full measure.

"Sathyavartha has departed as a true devotee of sathya (truth),"said Gurudev on the occasion of his samadhi.

A fascinating footnote is that at a time when caste system was rife in Kerala Satyavartha Swamikal who had come form a high-caste family, had joined Sree Narayana Guru, to become one of his greatest disciples.